Strengthening and weakening of relationships in cortical cultures: latency dependent?
نویسندگان
چکیده
Networks of cortical neurons were grown over multi electrode arrays to enable simultaneous measurement of signals from multiple neurons. Functional connectivity in cultured networks has been described by relationships between individual electrodes, based on conditional firing probabilities. In this study we investigated periods in which the strength of a relationship increased (strengthening) or decreased with time (weakening). We observed a slightly increased incidence of latencies around 20 ms during strengthening, while these latencies rarely coincided with weakening.
منابع مشابه
The Effect of Changing Interregional Relationships on Employment Changes: A Decomposition Analysis in Two-Regional Input- Output Model
According to the regional economic literature, interregional communication can play an important role in production, followed by production-related variables such as employment. For this reason, changing (strengthening or weakening) inter-regional communication can lead to changes in production and employment in the regions. Accordingly, the purpose of this study is to investigate the change of...
متن کاملEffect of Norepinephrine depletion on induction of experience dependent plasticity in male rat barrel cortex
Introduction: Barrel cortex of rats is a part of somatosensory cortex, which receives information from facial whiskers. Vibrisectomy by sensory deprivation leads to some changes in the barrel cortex, which have been known as experience dependent plasticity. On the other hand, Norepinephrine (NE) and locus coeruleus, which is the main source of NE, influenced response properties of cortical bar...
متن کاملEffect of locus ceruleus phasic electrical stimulation on responses of barrel cortical cells to controlled mechanical displacement in rats
Behavioral and electrophysiological evidences have shown that locus ceruleus (LC) is involved in different tasks including modulation of sensory processing and shift of attention. In the present study, single unit responses of barrel cortical cells was recorded following controlled mechanical displacement of the principal and peripheral vibrissae in adult rats (100 trials of 200 µm deflection f...
متن کاملModerate excitation leads to weakening of perceptual representations.
A fundamental goal of memory research is to specify the conditions that lead to the strengthening and weakening of neural representations. Several computational models of memory formation predict that learning effects should vary as a nonmonotonic function of the amount of excitation received by a neural representation. Specifically, moderate excitation should result in synaptic weakening, whil...
متن کاملDetermination of Relationships between the Ultrasound Velocity and the Physical Properties of Bovine Cortical Bone Femur
Accurate measurements of physical characteristics of bone are essential for diagnosis, assessment of change following treatment, and therefore, indirectly, for evaluation of new forms of therapy. This is particularly true of osteoporosis and aging skeleton, in which fractures occur easily. Methods: In this study an ultrasonic system was set-up and calibrated on Plexiglas tubes of variable thick...
متن کامل